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-   -   İntertrijinöz Psoriazis’in Tedavisi: (http://www.stetuskop.com/showthread.php?t=1965)

aygun_58 09-29-2009 23:30

İntertrijinöz Psoriazis’in Tedavisi:
 
Psoriazisli hastalarda gerçek insidans bilinmese de deri kıvrım yerlerinin tutulumu sıktır. Bu rapor intertrijinöz psoriazisin tedavisi ile ilgili çalışmaları özetlemektedir.
Amaç: Ulusal Psoriazis Kurumu Tıbbi Heyeti tedavi seçeneklerini değerlendirmek için geçici iş birliği ile bir araya toplandı. Amacımız intertrijinöz veya invers psoriazis tedavisinde bir ortak görüşe ulaşmaktı.
Metodlar: Deri kıvrım alanlarını tutan psoriazis ve tedavisi ile ilgili literatürdeki çalışmalar gözden geçirildi.
Kısıtlılıklar: İntertrijinöz psoriazis tedavisi ile ilgili delile dayalı az sayıda çalışma mevcuttur.
Bulgular: İnvers psoriazisin kısa süreli (2-4 haftalık) tedavisinde önerilen seçenek düşük-orta güçlü topikal steroidlerdir. Uzun süreli tedavi için topikal kalsipotrien (kalsipotriol) veya immünmodülatör ajanlar olan pimekrolimus veya takrolimustan biri tercih edilir.
Sonuçlar: Kısa süreli tedavide düşük-orta güçlü topikal steroidler ilk basamakta tercih edilir. Potansiyel riskleri en aza indirmek için kullanımları ya sınırlı bir süreyi kapsamalı (2-4 haftadan az) ya da uzun süreli tedavide etkili olan en düşük güçteki ilaç aralıklı olarak kullanılmalıdır. Kalsipotrien (kalsipotriol), pimekrolimus ve takrolimus, topikal steroidler kadar etkili olmasalar da uzun kullanımda riskleri daha az olduğundan, uygun durumda uzun süreli tedavide önerilmektedir

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